Meredith was elected to the Western Australian Parliament as the Member for Mirrabooka in March 2021. She later served as Parliamentary Secretary across Education, Aboriginal Affairs, Multicultural Interests, Treasury, Transport and Tourism before being promoted in March 2025 to Minister for Health and Mental Health.

Following the 2025 State Election, her electorate was renamed Girrawheen, one of the most diverse in WA. Meredith is deeply involved in the community and has built strong connections with local residents and organisations, reflecting her commitment to representing and supporting the people of her electorate.